In 2006, 454 collaborated with Swedish paleogeneticist Svante Pääbo to sequence the first million base pairs of the Neanderthal genome; the project would be completed four years later, albeit with some help from Illumina sequencing. Illumina and other subsequent NGS technologies rendered pyrosequencing non-competitive, and in 2013, 454 was shut down by Roche, which had acquired it six years earlier. The technology is still used today for some applications, but most importantly, it was the first commercially viable alternative to Sanger sequencing, and the first sequencing method that could be fully automated because it didn’t rely on gels or other tedious steps.
Крупнейшая нефтяная компания мира задумалась об альтернативе для морских перевозок нефти14:56
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Любов добавил, что необычно обильные осадки связаны с глобальным потеплением и циклонами со Средиземного моря, которых в эту зиму было особенно много. По словам фенолога, снег продолжит идти в регионе и в марте, но менее интенсивно.
12:11, 4 марта 2026Россия
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